The hereditary autosomal recessive disease ataxia telangiectasia (A-T) is caused by mutation in the DNA damage kinase ATM. ATM’s main function is to orchestrate DNA repair, thereby maintaining genomic ...
ATM is a powerful protein kinase, the function of which is lost in patients with the genomic instability syndrome ataxia-telangiectasia. The most documented function of ATM is mobilizing and ...
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