The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single ...

Therapeutic antibodies or immunoglobulins are becoming increasingly popular due to their targeted approach to treating various diseases, including cancer, autoimmune disorders, and infectious diseases ...

Researchers at Colorado State University have determined how to use artificial intelligence to modify antibodies so they act ...

Antibody humanization involves modifying antibodies from non-human sources, such as mice, to decrease their immunogenicity in human applications. While mouse monoclonal antibodies are specific, they ...

Understanding antibodies’ structure-function relationship, whether because of sequence modifications or changes in solution conditions, is crucial to understanding how functional changes occur.