New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

CalciMedica had been evaluating the therapy, called Auxora, in the Kourage trial of patients with stage 2 or 3 AKI with ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such ...

Please provide your email address to receive an email when new articles are posted on . An ongoing study showed improvements in SSc severity, disease-related pain, Raynaud’s symptoms and ...

New York University (NYU) researchers suggest that ORAI1 calcium channel activity in oral cancer cells could be targeted to reduce the growth of oral tumors and reduce pain, according to a study that ...

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a ...

Statins are a cornerstone of heart health, but muscle pain and weakness cause many patients to quit taking them. Scientists have now identified the precise molecular trigger behind these side effects.

Hand opening pill bottle Clearer guidelines for diuretic management in patients with chronic kidney disease are needed, according to investigators. Adding diuretics rather than calcium channel ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

Voltage‐gated calcium channels, particularly the CaV2.1 channels encoded by the CACNA1A gene, are central to cerebellar function and synaptic transmission. Dysfunction in these channels leads to a ...