When a muscle contracts, the parts of a sarcomere "shorten" and come closer together. Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events ...

Researchers find that deficiency in RPL3L, a ribosome expressed in heart and skeletal muscle, impairs cardiac contractility due to delayed mRNA translation Fukuoka, Japan—A team of researchers have ...

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice. The mutation was found to ...

This study investigates the role of a key interaction between Tropomyosin (Tpm) and Troponin T (TnT) in the regulation of cardiac muscle contraction, with a particular focus on understanding ...

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...