Using robots and click chemistry, scientists built potential active ingredients for future antibiotics that contain metal.

Collections of small molecules are used routinely in high-throughput screens to find new drug leads. In fact, from 1999 to 2008, 45 of the 50 Food and Drug Administration approvals for first-in-class ...

A 17-year-long intense competition to synthesize a fascinatingly weird and complex compound has finally ended. The first 25-step process for building the compound, Palau'amine, out of molecular ...

A laboratory experiment at NASA's Jet Propulsion Laboratory, Pasadena, Calif., simulating the atmosphere of Saturn's moon Titan suggests complex organic chemistry that could eventually lead to the ...