Aim: To demonstrate the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. To achieve real-time process control by establishing automated regulation of ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...

Advances in equipment, instrument, and control systems are enabling online monitoring of continuous API manufacturing. Continuous API manufacturing has the potential to provide tremendous benefits to ...

Advances in process analytical technology have been achieved, but significant challenges remain. Continuous API manufacturing has the potential to provide tremendous benefits to the pharmaceutical ...

Methods to Simultaneously Reduce Bioburden and Maintain Column Integrity, Explained Continuous bioprocessing is inevitably becoming the future of biomanufacturing. To date, several steps within a ...

In this course, you will learn to analyze data in terms of process stability and statistical control and why having a stable process is imperative prior to performing statistical hypothesis testing.

In biopharmaceutical manufacturing, consistency is vital but hard to achieve. Turning raw materials into safe, high-quality medicines requires stable processes. However, the living cellular expression ...

The extent to which products meet specifications needs to be systematically monitored in a production process. Product quality will typically be defined by two quantities: deviations from stated ...