As we get older, chemical marks on our DNA slowly shift. Now, a study reveals this 'drift' in gut stem cells is fueled by ...
DNA methylation in bacteria, primarily involving the addition of methyl groups to adenine or cytosine residues, constitutes a pivotal epigenetic mechanism that modulates gene expression without ...
"We find that epigenetic clocks based on the entropy of methylation states predict chronological age with similar accuracy as common approaches that are based on methylation levels of individual ...
A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 12, 2025, titled "DNA methylation entropy is a biomarker for aging." Researchers Jonathan Chan, Liudmilla Rubbi, and ...
“Our results suggest that rDNA promoter methylation and the age-related loss of active rDNA TU, which are a hallmark of the aging process, start only after reaching sexual maturity.” “Our results ...
A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled "Age-specific DNA ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...