DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that aid DNA in carrying out essential processes such as replication, repair, and ...

Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's ...

Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...

Researchers at The Institute of Cancer Research, London, have uncovered how the DNA repair enzyme XPF-ERCC1 is recruited to sites of damage and activated inside cells, resolving a long-standing ...

Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can lead to neurodegenerative disorders such as Motor Neurone Disease (MND).

Once failed in high school chemistry due to a teacher’s judgement, Tomas Lindahl later reshaped the same discipline. Awarded the 2015 Nobel Prize in Chemistry for his pioneering DNA repair research, ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

Scientists in Sweden and Norway have uncovered a promising way to spot Parkinson’s disease years—possibly decades—before its most damaging symptoms appear. By detecting subtle biological signals in ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...