Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...

PacBio has announced plans to enhance its methylation detection capabilities in HiFi sequencing by licensing advanced methods from Professor Dennis Lo and his team at The Chinese University of Hong ...

DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

Researchers have developed BayesCNA, a new method that detects cancer DNA at just 5% in blood samples, potentially improving ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models or cultured cells. To fully realize the potential to study biology at this unprecedented scale ...

Newborn babies admitted to the hospital's neonatal intensive care unit (NICU) rely on the quick decisions and rapid action of the medical team responsible for them. DNA testing is critical to ...

Researchers using cutting-edge environmental DNA (eDNA) technology have uncovered far greater biodiversity in eastern Ontario waterways than traditional monitoring methods detected over more than a ...