The FDA's orphan drug designation supports LP-284's development for soft tissue sarcomas, addressing significant unmet needs in this adult patient population. The FDA granted orphan drug designation ...
Intrinsic DILI: This is where a drug and/or drug metabolites induce liver toxicity in a predicted and dose-dependent manner. Most individuals show a response at some dose, and the toxicity levels are ...
A version of this story appeared in Volume 103, Issue 11 Chemists and chemical biologists just keep dreaming up new ways to interfere with biomolecules. That research frequently leads to promising ...
Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and ...
Lipids have become indispensable to modern drug delivery offering a versatile toolkit for the formulation and transport of therapeutic agents. Over the past two decades, the field has experienced ...
A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...
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