LNPs continue to dominate the spotlight in biopharma with three landmark acquisitions in the past six months, AbbVie/Capstan Therapeutics, Eli Lilly and Co/Verve Therapeutics and Bristol Myers ...
In the last 10 years, there has been significant development in computer simulation of pharmaceutical materials, processes and product performance. Gradually, more mechanistically based models are ...
Mechanistic models and hypothesis-driven strategies generate optimized efficient solutions for drug development, says Catalent’s Nathan Bennette at AAPS PharmSci ...
Process characterization and viral clearance validation are pivotal studies in biopharmaceutical manufacturing, particularly for monoclonal antibodies (mAbs) produced in mammalian systems, which carry ...
The primary components of LNP–RNA are ionizable lipids, cholesterol, PEGylated lipids, and phospholipids, which together form the nanoparticle, along with the active pharmaceutical ingredient, RNA.
Tooling and molding of automated processes such as transfer molding benefit greatly from flow and cure simulation-based computer-aided engineering, particularly for costly, high-temperature elastomers ...
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