Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

Professor Carsten Carlberg has published a comprehensive new textbook, Gene Regulation and Epigenetics: How Science Works, presenting the current understanding of gene regulation and epigenomics.

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...