The immune system's killer T cells are crucial in fighting viral infections. A fraction of them, called 'memory cells,' live on once infection is controlled to fight re-infection by the same virus.

During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or ...

Ingested antigens lead to the generation of effector T cells that secrete interleukin 4 (IL-4) rather than interferon-γ (IFN-γ) and are capable of influencing naive T cells in their immediate ...

Molecular mechanisms that control an immune cell's ability to remember have been identified by scientists. They found that in helper T (CD4+) cells, the proteins Oct1 and OCA-B work together to put ...

Helper T cells play an important role in the immune response against pathogens. The role of a particular subset of these immune cells was previously unclear. It's now been shown that T follicular ...

Kenta Shinoda, Koji Tokoyoda, Asami Hanazawa, Koji Hayashizaki, Sandra Zehentmeier, Hiroyuki Hosokawa, Chiaki Iwamura, Haruhiko Koseki, Damon J. Tumes, Andreas Radbruch, Toshinori Nakayama Proceedings ...

Germinal centre-independent memory B cells are generated from CD38 + GL7 + activated B cells. These memory B cells may maintain broad reactivity to the activating pathogen. B1a and B1b cells can ...

Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to ...