Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. These craniofacial anomalies occur because of defects in neural crest cells, whose ...

The neural crest is an extraordinary population of multipotent stem cells, unique to vertebrates, that plays a pivotal role in embryogenesis. Arising at the borders of the neural plate, these cells ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of detail in the ...

The Wei lab is interested in the regulation of cell signaling and tissue homeostasis by metalloproteinases and other proteins in development and disease. Project 1. The mechanisms of neural crest ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilized egg, starts to develop, ...

An illustration of zebrafish heart development, showing the migration of cells in the growing embryo after 17 hours, 1 day and 2 days to form the heart. Most heart cells come from the embryonic ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...