Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no cure and limited treatment options.

Brain functions stem from and rely on electrical signals created and propagated by neurons. As such, scientists measure electrical signals to study neuronal function at both single-cell and systemic ...

Researchers have developed the first activity-based maps of the prefrontal cortex, challenging traditional descriptions of ...

For more than a century, maps of the brain have been based on how brain tissue looks under the microscope.

Different neuronal cells have a diverse range of activity patterns, but the cause has remained unclear. In mice, maps of brain-wide inputs to individual neurons that do or do not show activity ...

Why is sleep so important for learning and memory? Neuroscientists from the Csicsvari group at the Institute of Science and Technology Austria (ISTA) provided new insight into this essential function ...

A study of nematodes by researchers at Nagoya University in Japan has found that aging-related decline in brain function is caused by the excessive activation of certain neurons over time, rather than ...

What if we could peer into the brain and watch how it organizes information as we act, perceive, or make decisions? A new study has introduced a method that does exactly this—not just by looking at ...

A new method of CCM using which connections between neurons can be inferred based on the causal relationships between spike train data. Understanding the brain’s functional architecture is a ...

Researchers found that excessively activated neurons over time, rather than decreased neuronal activity, cause aging-related decline in brain function in nematodes. A study of nematodes by researchers ...

Transgenic worm in which the splicing factor UNC-75, marked with the fluorophore mScarlet, reveals its expression throughout the nervous system. The worm was generated using CRISPR-Cas9 gene editing ...