All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk," may actually play powerful roles in regulating gene expression. Focusing ...
A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...
Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...
Vast swathes of the human genome remain a mystery to science. A new AI from Google DeepMind is helping researchers understand how these stretches of DNA impact the activity of other genes. While the ...
CRISPR-Cas9 has been widely adapted for use in transcriptional modulation and epigenetic engineering with deactivated Cas9 (dCas9) systems to enable CRISPR interference (CRISPRi) and CRISPR activation ...
New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...
Salk Institute researchers find new mode of epigenetic targeting, showing for the first time that genetic sequences can direct new DNA methylation patterns in plants LA JOLLA (November 21, 2025)—All ...
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic “junk”, may actually play powerful roles in regulating gene expression. A new ...