Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconvolution.

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

News Medical talks to Samuel Penwell and Winfried Wiegraebe about how the Vutara VXL enables robust, high-throughput 3D super-resolution via single-molecule localization, pairing bi-plane detection ...

Synapses in the forebrain were thought of as purely GABAergic, yet they contain minute numbers of glycine receptors, often in the single digits.

In a recent study published in Nature Communications, researchers developed a €350 smartphone-based microscope that can detect individual molecules. This brings super-resolution, research-grade ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

One method for visualizing dynamic biological processes is single particle tracking, a localization microscopy method. For this technique to be successful, several factors need to be considered, ...

Super-resolution microscopy, such as SMLM, has changed the way scientists visualize cellular structures by breaking the diffraction limits of traditional light microscopy. By pinpointing the exact ...

Celebrating three decades of global exchange in single-molecule spectroscopy and super-resolution microscopy PicoQuant GmbH reflects on the successful conclusion of its 30th International Workshop on ...

Accumulation of amyloid-beta (A-beta) peptides inhibiting normal brain function is a characteristic aspect of neurodegenerative disease, but how A-beta comes together and breaks apart as it does the ...