Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...

How would you summarize your study for a lay audience? Research on gastrointestinal diseases, especially cancer, has mainly looked at the epithelial cells, which line the surfaces of organs, are ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

Single-cell analyses have emerged as powerful tools for studying cellular heterogeneity and gene regulation. Single-cell chromatin accessibility sequencing (scCAS) is a key technology that enables the ...

As single-cell genomics experiments grow in size, so too does the need for sequencing. Several large projects have recently called on the relative newcomer to the NGS scene, Ultima Genomics, for their ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

At the heart of Toti-N-Seq lies an engineered protein, Stv-Fg, derived from modifying the natural glycan-binding protein Fbs1. This fusion protein binds non-selectively to all N-glycan types, enabling ...

Millions of people worldwide suffer from gum disease, yet we still don't fully understand how healthy gums turn into damaged, ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions ...