A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...

Bitter taste receptors, also known as TAS2Rs, are a distinct family of G protein-coupled receptors (GPCRs) originally recognised for their role in oral bitter taste perception. Recent research has ...

“Tasting Upside-Down - An Unusual Sensing Mechanism was Found in Human Bitter Sensing” A new study revealed that some bitter molecules target their sensor through binding simultaneously at two ...

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...

Cryo-EM map of the human sweet taste receptor (blue and green) changing shape as it binds a molecule that tastes sweet (red and green). NEW YORK — Our attraction to sugar has grown to an unhealthy ...

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body. At the same time, the anti-inflammatory ...

Why does coffee taste more bitter to some people than it does to others? Researchers have now come closer to answering this question. They have identified a new group of bitter compounds in roasted ...

In a recent study published in Scientific Reports, researchers investigated whether coronavirus disease 2019 (COVID-19)-related sensory deficiencies are associated with transcriptome changes in the ...