CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

DNA from a "prolific serial killer" discovered on a pair of paper bags have allowed Colorado authorities to solve a murder case from nearly 40 years ago, officials said. The body of Rhonda Marie ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Gerlinde Bigga does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

“The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we conceived of life itself. The X-ray crystallography by Rosalind Franklin ...

James D. Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped light the long fuse on a revolution in medicine, crimefighting, genealogy and ethics, has died, according to ...

Using comparative molecular biology with human cGAS – which actually inhibits DNA repair – the scientists found that the naked mole-rat's enzyme has four key changes that facilitate the important work ...

Breakthroughs, discoveries, and DIY tips sent six days a week. Terms of Service and Privacy Policy. The cassette tape. A staple of the Walkmans, car stereos, and ...

A new study shows that DNA forms coils under stress, not the tangled knots that scientists expected. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it ...

The Age of AI will rely on massive volumes of data that can be easily stored and retrieved—and bioscience may have an ingenious solution. A scientist examines a DNA (deoxyribonucleic acid) profile on ...

The human genome is chock full of what scientists once considered "junk DNA." This DNA is actually something called transposable elements, or TEs. These are repetitive sequences found in the genome ...