The authors established a useful syndetome differentiation protocol from human induced pluripotent stem cells, guided by single-cell transcriptomic analysis. Their findings could significantly impact ...

Vascular Health Unit, Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, Québec, Canada (J.H.B., H.P.Q., K.G., I.G., H.Z., S.S.D ...

PARIS--(BUSINESS WIRE)--#AI--Gustave Roussy partners with One Biosciences, a techbio company that harnesses single cell technology and AI to develop advanced precision diagnostics. The collaboration ...

As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ability to regenerate healthy blood and immune cells. By calming this cellular ...

The pineal gland is a central regulator of circadian rhythms and neuroendocrine homeostasis in primates, yet its cellular diversity and spatial regulatory logic remain poorly defined. By integrating ...

Chimeric antigen receptor T cell (CAR-T) therapy is considered one of the landmark achievements of modern medicine. The therapy involves harvesting a patient’s own immune cells, genetically ...

Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...

Oregon Health & Science University researchers have developed a first-of-its-kind method to predict cancer patient survival using advanced molecular data from individual cells. Survival analysis is ...

The biological connection between a pregnant woman and her developing baby—the human maternal–fetal interface—is a specialized, transient organ composed of uterine cells from the mother and fetal ...

Bulk RNA sequencing has advanced transcriptomic analysis across diverse biological systems, but averaging gene expression across cell populations can obscure important cellular differences.

Ulcerative colitis (UC) is driven by mucosal inflammation and epithelial injury. Single cell RNA sequencing (scRNA-seq) enables high resolution profiling of immune, stromal and epithelial compartments ...